Targetting αvβ3 and α5β1 integrins with Ecballium elaterium (L.) A. Rich. seed oil
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چکیده
منابع مشابه
Targetting alphavbeta3 and alpha5beta1 integrins with Ecballium elaterium (L.) A. Rich. seed oil
In the present study, the effect of Ecbalium elaterium seed oil on adhesion, migration and proliferation of human brain cancer cell line (U87) was determined. Treatment of U87 cell line with the seed oil resulted in strong inhibition of their adhesion to fibrinogen (Fg), fibronectin (Fn). It also reduced their migration and proliferation in a dose-dependent manner without being cytotoxic. Conco...
متن کاملA Micropropagation Protocol for Ecballium elaterium ( L . ) A . Rich
Introduction: Squirting cucumber, Ecballium elaterium (L.) A. Rich. (Cucurbitaceae), is a wild medicinal plant found abundantly in the Mediterranean region. It has been utilized as a rootstock for many cucurbitaceous crops, mainly attributed to its resistance to abiotic as well as biotic stress (2). Important pharmacological uses (1, 9) are attributed to the bitter principles, cucurbitacins (5)...
متن کاملA Toxicological and Phytochemical Study on the Iran’s Ecballium elaterium (L.) A. Rich.
Background: Ecballium elaterium is endemic to the northwestern Iran and its fruit is traditionally used for therapeutic purposes in Iran. The toxicological and phytochemical characteristics of the Iran’s Ecballium elaterium have not been investigated so far. Objective: Study on some toxicological and phytochemical features of the Iran’s Ecballium elaterium fruit 90% ethanol extract. Method: ...
متن کاملEcballium elaterium (L.) A. Rich. seed oil: Chemical composition and antiproliferative effect on human colonic adenocarcinoma and fibrosarcoma cancer cell lines
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متن کاملThe Cultivation and Cucurbitacin Content of Ecballium elaterium (L.)
Introduction: Although Ecballium elaterium (L.) A. Rich., is considered as a minor crop in the Cucurbitaceae family. However, its medicinal virtues (3, 8) and its resistance to pests and diseases (6, 7), have made the plant a suitable candidate to improve crop quality in Cucurbitaceae species. Cultivation studies were aimed at assessing the growth of the plant and the variation of cucurbitacins...
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ژورنال
عنوان ژورنال: Biomedicine & Pharmacotherapy
سال: 2016
ISSN: 0753-3322
DOI: 10.1016/j.biopha.2016.10.035